{"id":2862,"date":"2023-11-28T02:38:00","date_gmt":"2023-11-27T18:38:00","guid":{"rendered":"https:\/\/www.cib.cc\/?p=2862"},"modified":"2024-04-17T02:44:02","modified_gmt":"2024-04-16T18:44:02","slug":"%e4%b8%89%e5%90%af%e7%94%9f%e7%89%a9%e5%a4%9a%e5%8f%91%e6%80%a7%e9%aa%a8%e9%ab%93%e7%98%a4%e7%ae%a1%e7%ba%bf%e6%95%b0%e6%8d%ae%e5%b0%86%e4%ba%ae%e7%9b%b82023%e5%b9%b4%e7%be%8e%e5%9b%bd%e8%a1%80","status":"publish","type":"post","link":"https:\/\/www.cib.cc\/?p=2862","title":{"rendered":"\u4e09\u542f\u751f\u7269\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7ba1\u7ebf\u6570\u636e\u5c06\u4eae\u76f82023\u5e74\u7f8e\u56fd\u8840\u6db2\u75c5\u5e74\u4f1a"},"content":{"rendered":"\n<section style=\"box-sizing: border-box; font-style: normal; font-weight: 400; text-align: justify; font-size: 16px; visibility: visible;\"><section style=\"text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px 0px; box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; border-style: solid; border-width: 7px; border-color: rgb(238, 240, 255); padding: 22px 25px; box-sizing: border-box; visibility: visible;\"><section style=\"justify-content: flex-start; display: flex; flex-flow: row; margin: 0px 0px 10px; box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; vertical-align: bottom; width: auto; min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; align-self: flex-end; box-sizing: border-box; visibility: visible;\"><section style=\"font-size: 19px; margin: 0px 0%; text-align: center; box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; border-width: 1px; border-style: solid; border-color: rgb(27, 79, 149); background-color: rgb(27, 79, 149); width: 1.8em; height: 1.8em; line-height: 1.8em; border-radius: 100%; margin-left: auto; margin-right: auto; font-size: 12px; color: rgb(255, 255, 255); box-sizing: border-box; visibility: visible;\"><p style=\"margin: 0px; padding: 0px; box-sizing: border-box; visibility: visible;\">1<\/p><\/section><\/section><\/section><section style=\"display: inline-block; vertical-align: bottom; width: auto; align-self: flex-end; flex: 0 0 auto; min-width: 5%; max-width: 100%; height: auto; padding: 0px 0px 0px 10px; box-sizing: border-box; visibility: visible;\"><section style=\"text-align: justify; color: rgb(27, 79, 149); box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><p style=\"white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; visibility: visible;\"><strong style=\"box-sizing: border-box; visibility: visible;\">2023&nbsp;ASH Annual Meeting<\/strong><\/p><\/section><\/section><\/section><section style=\"text-align: justify; font-size: 14px; color: rgb(27, 79, 149); font-family: Optima-Regular, PingFangTC-light; box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><p style=\"text-indent: 2em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\">\u7b2c65\u5c4a\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a(ASH)\u5e74\u4f1a\u5c06\u4e8e2023\u5e7412\u67089-12\u65e5\u5728\u7f8e\u56fd\u5723\u5730\u4e9a\u54e5\u4e3e\u884c\uff0c\u8be5\u5e74\u4f1a\u662f\u5168\u7403\u8840\u6db2\u5b66\u9886\u57df\u6743\u5a01\u5b66\u672f\u76db\u4f1a\u3002ASH\u5e74\u4f1a\u4e0a\u5448\u73b0\u7684\u5b66\u672f\u62a5\u544a\u4ee3\u8868\u4e86\u8840\u6db2\u75c5\u9886\u57df\u7684\u6700\u91cd\u8981\u53ca\u524d\u6cbf\u7684\u7814\u7a76\u6210\u679c\u3002\u5168\u7403\u8fd1100\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u7684\u6570\u4e07\u540d\u8840\u6db2\u75c5\u4e13\u5bb6\u5b66\u8005\u53ca\u884c\u4e1a\u76f8\u5173\u4eba\u58eb\u5c06\u53c2\u4f1a\uff0c\u5206\u4eab\u5168\u7403\u524d\u6cbf\u7684\u8840\u6db2\u57fa\u7840\u548c\u4e34\u5e8a\u7814\u7a76\u8fdb\u5c55\uff0c\u5e76\u4ea4\u6d41\u5b9d\u8d35\u7684\u4e34\u5e8a\u5b9e\u8df5\u7ecf\u9a8c\u3002\u4e09\u542f\u751f\u7269\u5f00\u53d1\u7684iPSC\u6765\u6e90\u7684\u9776\u5411GPRC5D CAR-iNK\u4ea7\u54c1\u7684\u76f8\u5173\u4e34\u5e8a\u524d\u6570\u636e\u5c06\u5728ASH\u5e74\u4f1a\u4e0a\u53d1\u8868\uff0c\u6297\u4f53\u5e8f\u5217\u5408\u4f5c\u65b9\u4e3a\u5eb7\u6e90\u535a\u521b\u751f\u7269\u79d1\u6280\uff08\u5317\u4eac\uff09\u6709\u9650\u516c\u53f8\uff08\u7b80\u79f0\uff1a<a target=\"_blank\" href=\"http:\/\/cn.kyinno.com\" textvalue=\"\u5eb7\u6e90\u535a\u521b\" linktype=\"text\" imgurl=\"\" tab=\"outerlink\" data-linktype=\"2\" style=\"visibility: visible;\" rel=\"noopener\">\u5eb7\u6e90\u535a\u521b<\/a>\uff09\u3002<\/p><\/section><\/section><\/section><p style=\"white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\" powered-by=\"xiumi.us\"><br style=\"box-sizing: border-box; visibility: visible;\"><\/p><section style=\"display: flex; flex-flow: row; text-align: left; justify-content: center; margin: 10px 0% 4px; box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; vertical-align: top; width: auto; flex: 0 0 0%; height: auto; align-self: flex-start; box-sizing: border-box; visibility: visible;\"><section style=\"box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; width: 6px; height: 6px; vertical-align: top; overflow: hidden; border-width: 0px; border-radius: 10px; border-style: none; border-color: rgb(62, 62, 62); background-color: rgb(241, 92, 25); box-sizing: border-box; visibility: visible;\"><svg viewBox=\"0 0 1 1\" style=\"float: left; line-height: 0; width: 0px; vertical-align: top; visibility: visible;\"><\/svg><\/section><\/section><\/section><section style=\"display: inline-block; vertical-align: top; width: auto; flex: 0 0 0%; height: auto; align-self: flex-start; margin: 0px 10px; box-sizing: border-box; visibility: visible;\"><section style=\"box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; width: 6px; height: 6px; vertical-align: top; overflow: hidden; border-width: 0px; border-radius: 10px; border-style: none; border-color: rgb(62, 62, 62); background-color: rgb(247, 206, 42); box-sizing: border-box; visibility: visible;\"><svg viewBox=\"0 0 1 1\" style=\"float: left; line-height: 0; width: 0px; vertical-align: top; visibility: visible;\"><\/svg><\/section><\/section><\/section><section style=\"display: inline-block; vertical-align: top; width: auto; flex: 0 0 0%; height: auto; box-sizing: border-box; visibility: visible;\"><section style=\"box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block; width: 6px; height: 6px; vertical-align: top; overflow: hidden; border-width: 0px; border-radius: 10px; border-style: none; border-color: rgb(62, 62, 62); background-color: rgb(57, 219, 183); box-sizing: border-box; visibility: visible;\"><svg viewBox=\"0 0 1 1\" style=\"float: left; line-height: 0; width: 0px; vertical-align: top; visibility: visible;\"><\/svg><\/section><\/section><\/section><\/section><section style=\"box-sizing: border-box; visibility: visible;\" powered-by=\"xiumi.us\"><p style=\"text-indent: 2em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\"><span style=\"text-indent: 2em; font-family: Optima-Regular, PingFangTC-light; font-size: 15px; color: rgb(0, 0, 0); box-sizing: border-box; visibility: visible;\">\u591a\u53d1\u6027\u9aa8\u9ad3\u7624(multiple myeloma, MM)\u662f\u4e00\u79cd\u514b\u9686\u6d46\u7ec6\u80de\u5f02\u5e38\u589e\u6b96\u7684\u6076\u6027\u75be\u75c5\uff0c\u662f\u4e00\u79cd\u8840\u6db2\u7cfb\u7edf\u5e38\u89c1\u6076\u6027\u80bf\u7624\uff0c\u591a\u53d1\u4e8e\u4e2d\u8001\u5e74\uff0c\u76ee\u524d\u5c1a\u65e0\u6cd5\u6cbb\u6108\u3002<\/span><\/p><p style=\"text-indent: 2em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\"><span style=\"text-indent: 2em; font-family: Optima-Regular, PingFangTC-light; font-size: 15px; color: rgb(0, 0, 0); box-sizing: border-box; visibility: visible;\">\u4e09\u542f\u751f\u7269\u5229\u7528\u9ad8\u6548\u7684iPSC\u91cd\u7f16\u7a0b\u53ca\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0\u3001iPSC\u5411NK\u7ec6\u80de\u7684\u9ad8\u6548\u5206\u5316\u5e73\u53f0\u3001iNK\u5927\u89c4\u6a21\u6269\u589e\u5e73\u53f0\uff08\u5355\u4e2aiPSC\u7ecf\u5206\u5316\u6269\u589e\u53ef\u83b7\u5f97\u8d85\u8fc7\u767e\u4e07\u4e2aiNK\u7ec6\u80de\uff09\u3001iNK\u51bb\u5b58\u590d\u82cf\u5e73\u53f0\u4ee5\u53ca\u4f53\u5916\u836f\u6548\u8bc4\u4ef7\u5e73\u53f0\uff0c\u7ed3\u5408\u5eb7\u6e90\u535a\u521b\u63d0\u4f9b\u7684\u9ad8\u4eb2\u548c\u529b\u7ed3\u5408GPRC5D\u7684\u6297\u4f53\u5e8f\u5217\uff0c\u5f00\u53d1\u51fa\u9776\u5411GPRC5D\u7684iPSC\u6765\u6e90\u7684CAR-NK\u7ec6\u80de\uff0c\u76f8\u5173\u4e34\u5e8a\u524d\u6570\u636e\u5c06\u5728\u7b2c65\u5c4a\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a(ASH)\u5e74\u4f1a\uff082023 ASH Annual Meeting\uff09\u4e0a\u4ee5\u5899\u62a5\u5f62\u5f0f\u53d1\u5e03\u3002<\/span><\/p><p style=\"text-indent: 2em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\"><span style=\"font-family: Optima-Regular, PingFangTC-light; font-size: 15px; color: rgb(0, 0, 0); box-sizing: border-box; visibility: visible;\">\u672c\u6b21\u62a5\u544a\u7684\u9898\u76ee\u4e3a\u201cEfficacy of Human iPSC-Derived CAR-NK Cells Targeting Multiple Myeloma Cells\u201d\u3002\u76f8\u5173\u62a5\u544a\u663e\u793a\uff0c\u8be5iPSC\u6765\u6e90\u7684CAR-NK\u7ec6\u80de\u7eaf\u5ea6\u8d85\u8fc799%\uff0c\u4e14\u4e0d\u8868\u8fbe\u237a\u03b2TCR\u53ca\u01b3\ud835\udec5TCR\u5206\u5b50\u3002NK\u7ec6\u80de\u6fc0\u6d3b\u53d7\u4f53\uff08NKG2D\uff0cNKp30\uff09\u53ca\u5171\u523a\u6fc0\u56e0\u5b50\uff08CD226\uff0cCD244\uff09\u8868\u8fbe\u5747\u8d85\u8fc796%\u4ee5\u4e0a\u3002\u6b64\u5916\uff0c\u4ea7\u54c1\u7684\u5355\u7ec6\u80de\u6d4b\u5e8f\u4e2d\u4e5f\u53d1\u73b0\u8d85\u8fc793%\u7684\u7ec6\u80de\u88ab\u6ce8\u91ca\u4e3aNK\u7c7b\u7ec6\u80de\u3002<\/span><\/p><p style=\"text-indent: 2em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\"><span style=\"font-family: Optima-Regular, PingFangTC-light; font-size: 15px; color: rgb(0, 0, 0); box-sizing: border-box; visibility: visible;\">\u5728\u4f53\u5916\u8bd5\u9a8c\u4e2d\uff0c\u6297GPRC5D CAR\u5c06iNK\u7ec6\u80de\u6740\u4f24\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08MM\uff09\u80bf\u7624\u7ec6\u80deNCI-H929-Luc\u7684\u6d3b\u6027\u63d0\u5347\u7ea69\u500d\uff0c\u660e\u663e\u4f18\u4e8e\u6297BCMA CAR\u3002\u6570\u636e\u663e\u793a\uff1a\u51bb\u5b58\u590d\u82cf\u540e\u7684\u4ea7\u54c1\u5bf9GPRC5D\u9ad8\u8868\u8fbe\u7684MM\u80bf\u7624\u7ec6\u80de\uff08NCI-H929\u548cMM.1S\uff09,\u4ee5\u53ca\u4f4e\u4e30\u5ea6\u8868\u8fbeGPRC5D \u7684MM\u80bf\u7624\u7ec6\u80deOPM2\u5747\u4fdd\u6301\u826f\u597d\u7684\u6740\u4f24\u6d3b\u6027\u3002<\/span><\/p><p style=\"text-indent: 2em; white-space: normal; margin: 0px; padding: 0px; box-sizing: border-box; text-align: left; visibility: visible;\"><span style=\"font-family: Optima-Regular, PingFangTC-light; font-size: 15px; color: rgb(0, 0, 0); box-sizing: border-box; visibility: visible;\">\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u8be5\u4ea7\u54c1\u53ef\u4ee5\u51b7\u51bb\u4fdd\u5b58\uff0c\u590d\u82cf\u540e\u7684\u7ec6\u80de\u6d3b\u7387\u53ca\u5f97\u7387\u5747\u8d85\u8fc790%\uff0c\u66f4\u4fbf\u4e8e\u4e34\u5e8a\u5e94\u7528\u3002\u5728\u6a21\u62df\u533b\u9662\u7ed9\u836f\u7684\u60c5\u666f\u4e0b\uff0c\u8fd0\u8f932000 km\u7684\u51bb\u5b58CAR-iNK\u4ea7\u54c1\u7ecf\u590d\u82cf\u540e\u5355\u6b21\u7ed9\u836f\uff0c\u53ef\u663e\u8457\u964d\u4f4eXenograft\u79fb\u690d\u6a21\u578b\u5c0f\u9f20\u7684\u80bf\u7624\u8d1f\u8377\uff0c\u5e76\u63d0\u5347\u5c0f\u9f20\u751f\u5b58\u7387\u3002<\/span><\/p><p style=\"text-indent: 2em;white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;text-align: left;\"><span style=\"font-family: Optima-Regular, PingFangTC-light;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box;\">\u57fa\u4e8e\u8be5\u9879\u76ee\uff0c\u4e09\u542f\u751f\u7269\u7ed3\u5408\u81ea\u8eab\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0\u4f18\u52bf\u8fdb\u4e00\u6b65\u5f00\u53d1\u51fa\u9488\u5bf9MM\u7684\u9996\u4e2aiPSC\u6765\u6e90\u7684CAR-NK\u4ea7\u54c1CIB-315\u3002\u8be5\u4ea7\u54c1\u4e3a\u7b2c\u56db\u4ee3CAR-NK\u4ea7\u54c1\uff0c\u8868\u8fbe\u6709\u7279\u5f02\u6027\u8bc6\u522b\u80bf\u7624\u6297\u539f\u7684CAR\u5206\u5b50\uff0c\u63d0\u5347ADCC\u6548\u5e94\u7684CD16\u53d8\u4f53\uff0c\u5e76\u4e14\u6572\u9664\u4e86\u76f8\u5173\u57fa\u56e0\u4ee5\u63d0\u5347NK\u7ec6\u80de\u6d3b\u6027\u3001\u6301\u4e45\u6027\uff0c\u4ee5\u53ca\u9632\u6b62\u81ea\u76f8\u6b8b\u6740\u3002\u4f53\u5185\u5b9e\u9a8c\u8bc1\u5b9e\uff0c\u8be5\u4ea7\u54c1\u5728\u8377\u7624\u5c0f\u9f20\u4f53\u5185\u53ef\u5b9e\u73b0\u7a33\u5b9a\u6269\u589e\uff0c\u8f93\u6ce82\u5468\u540e\u5c0f\u9f20\u5916\u5468\u8840\u5185\u53ef\u68c0\u6d4b\u52302.9E5 CAR copies\/\u00b5g DNA\uff0c\u76f8\u5bf9\u4e8eday 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hidden;border-width: 0px;border-radius: 10px;border-style: none;border-color: rgb(62, 62, 62);background-color: rgb(241, 92, 25);box-sizing: border-box;\"><svg viewBox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section><\/section><\/section><section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;align-self: flex-start;margin: 0px 10px;box-sizing: border-box;\"><section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-width: 0px;border-radius: 10px;border-style: none;border-color: rgb(62, 62, 62);background-color: rgb(247, 206, 42);box-sizing: border-box;\"><svg viewBox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section><\/section><\/section><section style=\"display: inline-block;vertical-align: top;width: auto;flex: 0 0 0%;height: auto;box-sizing: border-box;\"><section style=\"box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;width: 6px;height: 6px;vertical-align: top;overflow: hidden;border-width: 0px;border-radius: 10px;border-style: none;border-color: rgb(62, 62, 62);background-color: rgb(57, 219, 183);box-sizing: border-box;\"><svg viewBox=\"0 0 1 1\" style=\"float:left;line-height:0;width:0;vertical-align:top;\"><\/svg><\/section><\/section><\/section><\/section><section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin: 10px 0px 0px;box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 7px;border-color: rgb(238, 240, 255);padding: 22px 25px;box-sizing: border-box;\"><section style=\"justify-content: flex-start;display: flex;flex-flow: row;margin: 0px 0px 10px;box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;max-width: 100%;flex: 0 0 auto;height: auto;align-self: flex-end;box-sizing: border-box;\"><section style=\"font-size: 19px;margin: 0px 0%;text-align: center;box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(27, 79, 149);background-color: rgb(27, 79, 149);width: 1.8em;height: 1.8em;line-height: 1.8em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 12px;color: rgb(255, 255, 255);box-sizing: border-box;\"><p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">2<\/p><\/section><\/section><\/section><section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px 0px 0px 10px;box-sizing: border-box;\"><section style=\"text-align: justify;color: rgb(27, 79, 149);font-family: Optima-Regular, PingFangTC-light;box-sizing: border-box;\" powered-by=\"xiumi.us\"><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u62a5\u544a\u8be6\u60c5<\/strong><\/p><\/section><\/section><\/section><section style=\"text-align: justify;font-size: 14px;color: rgb(27, 79, 149);font-family: Optima-Regular, PingFangTC-light;box-sizing: border-box;\" powered-by=\"xiumi.us\"><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;text-align: left;\">Session Name: 703. Cellular Immunotherapies: Basic and Translational: Poster III<br style=\"box-sizing: border-box;\"><\/p><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;text-align: left;\">Session Date: Monday, December 11, 2023<\/p><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;text-align: left;\">Presentation Time: 6:00 PM &#8211; 8:00 PM<\/p><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;text-align: left;\">Location: San Diego Convention Center, Halls G-H<\/p><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;text-align: left;\">Title: Efficacy of Human iPSC-Derived CAR-NK Cells Targeting Multiple Myeloma Cells<\/p><\/section><\/section><\/section><section style=\"text-align: left;justify-content: flex-start;display: flex;flex-flow: row;margin: 10px 0px 0px;box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;width: 100%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;border-style: solid;border-width: 7px;border-color: rgb(238, 240, 255);padding: 22px 25px;box-sizing: border-box;\"><section style=\"justify-content: flex-start;display: flex;flex-flow: row;margin: 0px 0px 10px;box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;vertical-align: bottom;width: auto;min-width: 5%;max-width: 100%;flex: 0 0 auto;height: auto;align-self: flex-end;box-sizing: border-box;\"><section style=\"font-size: 19px;margin: 0px 0%;text-align: center;box-sizing: border-box;\" powered-by=\"xiumi.us\"><section style=\"display: inline-block;border-width: 1px;border-style: solid;border-color: rgb(27, 79, 149);background-color: rgb(27, 79, 149);width: 1.8em;height: 1.8em;line-height: 1.8em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 12px;color: rgb(255, 255, 255);box-sizing: border-box;\"><p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">3<\/p><\/section><\/section><\/section><section style=\"display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px 0px 0px 10px;box-sizing: border-box;\"><section style=\"text-align: justify;color: rgb(27, 79, 149);box-sizing: border-box;\" powered-by=\"xiumi.us\"><p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5173\u4e8e\u6211\u4eec<\/strong><\/p><\/section><\/section><\/section><section style=\"text-align: justify;font-size: 14px;color: rgb(27, 79, 149);font-family: Optima-Regular, PingFangTC-light;box-sizing: border-box;\" powered-by=\"xiumi.us\"><p style=\"text-indent: 2em;white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4e09\u542f\u751f\u7269\u662f\u4e00\u5bb6\u7814\u53d1\u9a71\u52a8\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u56fd\u5bb6\u7ea7\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u57fa\u4e8e\u4ebaiPSC\u7684\u901a\u7528\u578b\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u3002\u4e09\u542f\u751f\u7269\u662f\u56fd\u5185\u6700\u65e9\u4ece\u4e8biPSC\u7814\u7a76\u548c\u4e34\u5e8a\u8f6c\u5316\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\u4e4b\u4e00\uff0c\u5177\u6709\u4e30\u5bcc\u7684\u5546\u4e1a\u7ea7\u522biPSC\u4e09\u7ea7\u5e93\u548c\u591a\u9879iPSC\u76f8\u5173\u7684\u77e5\u8bc6\u4ea7\u6743\u53caKnowhow\uff1b\u540c\u65f6\uff0c\u4e09\u542f\u751f\u7269\u5df2\u5efa\u6210\u4e34\u5e8a\u7ea7iPSC\u7ec6\u80de\u5e93\u7528\u4e8e\u7ec6\u80de\u65b0\u836f\u5f00\u53d1\u3002<\/p><p style=\"text-indent: 2em;white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4e09\u542f\u751f\u7269\u5df2\u5efa\u7acbiPSCell<sup style=\"font-size: 11px;box-sizing: border-box;\">\u00ae<\/sup> iPSC\u6838\u5fc3\u6280\u672f\u5e73\u53f0\uff0c\u9ad8\u6548\u591a\u4f4d\u70b9\u4e00\u6b65\u6cd5\u57fa\u56e0\u4fee\u9970\u5e73\u53f0\uff0cPSCDiffer<sup style=\"font-size: 11px;box-sizing: border-box;\">\u00ae<\/sup>\u9ad8\u7eaf\u5ea6\u5927\u89c4\u6a21\u5b9a\u5411\u5206\u5316\u53ca\u6269\u589e\u5e73\u53f0\uff0c\u5e76\u4ee5\u6b64\u5efa\u7acb\u4e86\u57fa\u4e8eiPSC\u7684\u901a\u7528\u578b\u514d\u75ab\u7ec6\u80de\u4e34\u5e8a\u4ea7\u54c1\u5f00\u53d1\u5e73\u53f0\u3002\u901a\u8fc7\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u5b9a\u5411\u5206\u5316\u6280\u672f\uff0ciPSC\u53ef\u88ab\u9ad8\u6548\uff08&gt;99%\u7eaf\u5ea6\uff09\u5206\u5316\u4e3a\u9020\u8840\u5e72\u7ec6\u80de\u53ca\u7956\u7ec6\u80de\uff08iHSPC\uff09\u5e76\u83b7\u5f97\u8fd1200\u500d\u6269\u589e\u3002\u4e09\u542f\u5df2\u5efa\u7acb\u6807\u51c6\u64cd\u4f5c\u6d41\u7a0b\u7528\u4e8e\u5c06iHSPC\u5206\u5316\u4e3a\u6cbb\u7597\u591a\u79cd\u75be\u75c5\u7684\u901a\u7528\u578b\u514d\u75ab\u7ec6\u80de\uff0c\u5982NK\u3001\u5de8\u566c\u7ec6\u80de\u3001T\u7ec6\u80de\u3001\u4e2d\u6027\u7c92\u7ec6\u80de\u3001\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u7b49\u591a\u4e2a\u9020\u8840\u8c31\u7cfb\u3002\u5176\u4e2d\uff0cCAR-iPSC-NK\u65b9\u5411\u76ee\u524d\u6709\u591a\u4e2a\u7ba1\u7ebf\u5904\u4e8e\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u72ec\u7279\u7684iHSPC\u548ciNK\u5206\u5316\u53ca\u6269\u589e\u6280\u672f\u672a\u6765\u5c06\u4e3a\u75c5\u4eba\u63d0\u4f9b\u5b89\u5168\u3001\u6709\u6548\u3001\u53ef\u53ca\u6027\u597d\u3001\u6210\u672c\u53ef\u63a7\u7684\u4e34\u5e8a\u6cbb\u7597\u4ea7\u54c1\u3002<\/p><\/section><\/section><\/section><\/section>\n","protected":false},"excerpt":{"rendered":"<p>1 2023&nbsp;ASH Annual Meeting \u7b2c65\u5c4a\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a(ASH)\u5e74\u4f1a\u5c06\u4e8e2023\u5e74 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2863,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[],"class_list":["post-2862","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/www.cib.cc\/index.php?rest_route=\/wp\/v2\/posts\/2862","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cib.cc\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cib.cc\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cib.cc\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cib.cc\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2862"}],"version-history":[{"count":0,"href":"https:\/\/www.cib.cc\/index.php?rest_route=\/wp\/v2\/posts\/2862\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cib.cc\/index.php?rest_route=\/wp\/v2\/media\/2863"}],"wp:attachment":[{"href":"https:\/\/www.cib.cc\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2862"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cib.cc\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2862"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cib.cc\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2862"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}