{"id":8411,"date":"2025-06-11T11:03:36","date_gmt":"2025-06-11T03:03:36","guid":{"rendered":"https:\/\/www.cib.cc\/?p=8411"},"modified":"2025-06-18T16:08:43","modified_gmt":"2025-06-18T08:08:43","slug":"isscr-2025-%e5%b9%b4%e4%bc%9a-%e4%b8%89%e5%90%af%e7%94%9f%e7%89%a9%e5%b1%95%e7%a4%ba%e5%9f%ba%e4%ba%8e-ipsc-%e7%9a%84%e9%98%bf%e5%b0%94%e5%85%b9%e6%b5%b7%e9%bb%98%e7%97%87%e5%88%9b%e6%96%b0%e6%a8%a1","status":"publish","type":"post","link":"https:\/\/www.cib.cc\/?p=8411","title":{"rendered":"ISSCR 2025 \u5e74\u4f1a | \u4e09\u542f\u751f\u7269\u5c55\u793a\u57fa\u4e8e iPSC \u7684\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u521b\u65b0\u6a21\u578b"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"8411\" class=\"elementor elementor-8411\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36bc51c e-flex e-con-boxed e-con e-parent\" data-id=\"36bc51c\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-336a2a5 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"336a2a5\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"731\" src=\"https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1-1024x731.jpg\" class=\"attachment-large size-large wp-image-8469\" alt=\"\" srcset=\"https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1-1024x731.jpg 1024w, https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1-300x214.jpg 300w, https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1-768x548.jpg 768w, https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1.jpg 1264w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">\u5e74\u4f1a\u6d77\u62a5  https:\/\/www.isscr.org\/upcoming-programs\/isscr-2025<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1f7a173 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"1f7a173\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<section><p><strong>Presentation Title: \u00a0An iPSC-Based High\u00a0<\/strong><strong style=\"font-family: inherit; font-size: inherit; font-style: inherit; font-variant-ligatures: inherit; font-variant-caps: inherit;\">Throughput Drug Screening Platform for\u00a0<\/strong><strong style=\"font-family: inherit; font-size: inherit; font-style: inherit; font-variant-ligatures: inherit; font-variant-caps: inherit;\">Alzheimer&#8217;s Disease<\/strong><\/p><p>Presentation Date: \u00a06\/11\/2025<\/p><p>Presentation Session: Poster Session 1 (ODD)<\/p><p>Presentation Start Time: 4:00:00 PM<\/p><p>Poster Number: \u00a0W1225<\/p><\/section>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-215d14a e-con-full e-flex e-con e-child\" data-id=\"215d14a\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c581cbf elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"c581cbf\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>2025 \u5e74 6 \u6708 11 \u65e5\u81f3 14 \u65e5\uff0c\u56fd\u9645\u5e72\u7ec6\u80de\u7814\u7a76\u5b66\u4f1a\uff08ISSCR\uff09\u5e74\u4f1a\u5728\u4e2d\u56fd\u9999\u6e2f\u56fd\u9645\u4f1a\u5c55\u4e2d\u5fc3\u4e3e\u884c\u3002\u4f5c\u4e3a\u5168\u7403\u5e72\u7ec6\u80de\u4e0e\u518d\u751f\u533b\u5b66\u9886\u57df\u6700\u5177\u6743\u5a01\u6027\u7684\u5b66\u672f\u76db\u4f1a\uff0c\u672c\u6b21\u5e74\u4f1a\u5438\u5f15\u4e86\u6765\u81ea 75 \u4e2a\u56fd\u5bb6\u7684 4000 \u591a\u540d\u4e13\u4e1a\u4eba\u58eb\uff0c\u6db5\u76d6 250 \u591a\u573a\u5b66\u672f\u62a5\u544a\u53ca 1400 \u591a\u9879\u6d77\u62a5\u5c55\u793a\uff0c\u805a\u7126\u5e72\u7ec6\u80de\u7814\u7a76\u3001\u57fa\u56e0\u6cbb\u7597\u53ca\u518d\u751f\u533b\u5b66\u7684\u6700\u65b0\u7a81\u7834\u3002<\/p><p>\u4e09\u542f\u751f\u7269\u5f88\u8363\u5e78\u80fd\u591f\u53c2\u52a0\u6b64\u6b21\u76db\u4f1a\uff0c\u5e76\u4ee5Poster presentation\u5f62\u5f0f\u5c55\u793a\u4e86\u516c\u53f8\u5728\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u7814\u7a76\u9886\u57df\u7684\u521b\u65b0\u6210\u679c\u2014\u2014\u57fa\u4e8e iPSC\uff08\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff09\u7684\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\uff08Alzheimer&#8217;s Disease\uff0cAD\uff09\u521b\u65b0\u6a21\u578b\u3002<\/p><p>\u8be5\u6a21\u578b\u662f\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u7684iPSC\u6784\u5efa\u7684\u4e00\u7cfb\u5217AD\u76f8\u5173\u75be\u75c5\u6a21\u578b\uff0c\u53ef\u5728\u4f53\u5916\u6a21\u62df\u5bb6\u65cf\u6027AD\u7684\u5173\u952e\u75c5\u7406\u7279\u5f81\uff0c\u4e3a\u6df1\u5165\u7814\u7a76\u75be\u75c5\u7684\u53d1\u75c5\u673a\u5236\u548c\u8fdb\u5c55\u63d0\u4f9b\u4e86\u521b\u65b0\u6027\u7684\u5de5\u5177\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc8dca7 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"dc8dca7\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"823\" height=\"355\" src=\"https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1750233793882-1.jpg\" class=\"attachment-large size-large wp-image-8475\" alt=\"\" srcset=\"https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1750233793882-1.jpg 823w, https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1750233793882-1-300x129.jpg 300w, https:\/\/www.cib.cc\/wp-content\/uploads\/2025\/06\/1750233793882-1-768x331.jpg 768w\" sizes=\"(max-width: 823px) 100vw, 823px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-98b9e1e elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"98b9e1e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u4e0e\u6765\u81ea\u6563\u53d1\u578b\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\uff08SAD\uff09\u75c5\u4eba\u6765\u6e90\u7684iPSCs\u7684\u901a\u7528\u795e\u7ecf\u5143\u76f8\u6bd4\uff0c\u6765\u81ea\u5e26\u6709\u5916\u6e90 BACE1 \u8868\u8fbe\u7684 iPSCs\uff08iPSM0039\uff09\u7684\u901a\u7528\u795e\u7ecf\u5143\u663e\u8457\u52a0\u5267\u4e86\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u76f8\u5173\u8868\u578b\uff0c\u8868\u73b0\u4e3a A\u03b242 \u548c A\u03b240 \u5206\u6ccc\u589e\u52a0\u3002\u6211\u4eec\u8fdb\u4e00\u6b65\u5229\u7528\u8be5 iPSC \u884d\u751f\u7684\u795e\u7ecf\u5143\u6784\u5efa\u4e86\u4e00\u4e2a\u7528\u4e8e\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u7684\u9ad8\u901a\u91cf\u836f\u7269\u7b5b\u9009\u5e73\u53f0\uff0c\u901a\u8fc7\u7b5b\u9009\u4e2d\u836f\u6765\u6e90\u768468\u4e2a\u5929\u7136\u5316\u5408\u7269\uff0c4 \u4e2a\u5929\u7136\u5316\u5408\u7269\u663e\u793a\u51fa\u663e\u8457\u7684\u964d\u4f4e A\u03b242 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\u4e13\u5229\u6388\u6743\uff08US11834648B2\uff09\uff0c\u6211\u4eec\u6b22\u8fce\u81f4\u529b\u4e8e\u8be5\u9886\u57df\u79d1\u5b66\u5bb6\u548c\u836f\u7269\u5f00\u53d1\u4f01\u4e1a\u901a\u8fc7\u5408\u4f5c\u6216\u6388\u6743\u4f7f\u7528\u8be5\u6a21\u578b\u5f00\u53d1 AD \u521b\u65b0\u7597\u6cd5\uff0c\u4e3a\u63d0\u5347 AD \u75c5\u4eba\u751f\u5b58\u8d28\u91cf\u8d21\u732e\u529b\u91cf\u3002<\/p><p>ISSCR 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data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u4e09\u542f\u751f\u7269\uff08Cell Inspire Biotechnology, CIB\uff09\u6210\u7acb\u4e8e2013\u5e74\uff0c\u662f\u4e2d\u56fd\u9996\u5bb6\u4e13\u6ce8\u4e8e\u5546\u4e1a\u7ea7\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u7cfb\u751f\u4ea7\u3001iPSC \u57fa\u56e0\u7f16\u8f91\u53ca iPSC \u5b9a\u5411\u5206\u5316\u4e3a\u591a\u79cd\u539f\u4ee3\u7ec6\u80de\u7684\u516c\u53f8\u3002\u4e09\u542f\u751f\u7269\u81ea\u6210\u7acb\u4ee5\u6765\uff0c\u5df2\u5728\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u9886\u57df\u79ef\u7d2f\u4e86\u4e30\u5bcc\u7684\u7814\u53d1\u6210\u679c, \u5efa\u7acb\u4e86\u4e94\u4e2a\u6838\u5fc3\u6280\u672f\u5e73\u53f0: iPSC \u5236\u4f5c\u5e73\u53f0, iPSC \u57fa\u56e0\u7f16\u8f91\u5e73\u53f0, iPSC 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